STEP 1: Review of Available Safety Information
The Human Health Risk Assessment of individual ingredients is the foundation for the risk assessment of the products that contain them. Therefore, the first step in a risk assessment for new ingredients is a review of all available safety data from various sources. These sources include, but are not limited to: public on-line databases, toxicological reviews, information from suppliers, results from previously conducted testing on this or related substances and information about the metabolism 
of this type of substance.
Once this review has been completed and the information analysed - a process that may take anywhere from several days to several weeks - a trained risk assessment scientist will make a preliminary risk assessment. The result of this exercise is the identification of missing information ("data gaps") and an understanding of which end points, if any, may require further evaluation. This helps the scientist to determine which toxicological areas should receive higher priority, and how the testing program should be designed.
of this type of substance.Once this review has been completed and the information analysed - a process that may take anywhere from several days to several weeks - a trained risk assessment scientist will make a preliminary risk assessment. The result of this exercise is the identification of missing information ("data gaps") and an understanding of which end points, if any, may require further evaluation. This helps the scientist to determine which toxicological areas should receive higher priority, and how the testing program should be designed.
Read about the next step: 
Exposure Assessment
Exposure Assessment